While the U.S. has reported over 23 million cases and more than 385,000 deaths, the entire continent of Africa has just 3% of the world’s COVID-19 cases and only about 4% of virus-related deaths. Not only does Africa have almost four times the population but it has just a fraction of the health care resources. Despite the recent surge infections, and the discovery of the new E484K mutation in South Africa, what did the region initially do right?